Description
Chelaskin performs immediate removal of bruises, post-filler, post-mesotherapy, post-sclerotherapy, postlaser, post skin-roller, post-dermoabrasion, post-rhinoplasty, and so on…
It allows to extend filler’s half-life, thanks tothe anti-metal protease chelating action.
It performs an efficient purifying action,removing all dermal deposits of heavy metals (iron, lead and zinc) which concur to skin aging.
The Lactoferrin is a glycoprotein mainly present in breast milk, but is present in many secretions such as tears and saliva with a strong chelating action of the iron.
The Lactoferrin is a chelator endogenous which belongs to the family of transferrins.
The Lactoferrin is able to chelate iron (two atoms) at neutral or alkaline pH and of release at acidic pH.
The three-dimensional structure of lactoferrin, consists of a single polypeptide chain of 692 amino acids, is organized in two globular lobes joined by a alpha-helix.
Each of the two lobes of the protein consists of two domains. The protein is structured in such a way such as to have a single binding site for the iron for each lobe, located in each of the faces internal of intra-dominial space.
The binding properties of lactoferrin are developed through the combined action of 4 residues amino acid identical for each lobe and and include, in addition to the ferric ion, a counter ion (normally a CO32-), synergistic for each Fe3 +. This set of ligands is chemically and geometrically ideal for a high binding affinity reversible with iron and the presence of a non-protein element (CO3 2 -) seems to be a necessary condition both for the bond, and for the release of iron.
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